Mutational analysis of hedgehog signaling pathway genes in human malignant mesothelioma.

Mutational analysis of hedgehog signaling pathway genes in human malignant mesothelioma.

BACKGROUND: The Hedgehog (HH) signaling pathway is critical for embryonic development and adult homeostasis. Recent studies have identified regulatory roles for this pathway in certain cancers with mutations in the HH pathway genes. The extent to which mutations of the HH pathway genes are involved...

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Bibliographic Details
Main Authors: Chuan Bian Lim, Cecilia M Prêle, Hui Min Cheah, Yuen Yee Cheng, Sonja Klebe, Glen Reid, D Neil Watkins, Svetlana Baltic, Philip J Thompson, Steven E Mutsaers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3691204?pdf=render

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http://europepmc.org/articles/PMC3691204?pdf=render

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