TNFα/TNFR2 signaling pathway: an active immune checkpoint for mesenchymal stem cell immunoregulatory function

TNFα/TNFR2 signaling pathway: an active immune checkpoint for mesenchymal stem cell immunoregulatory function

Abstract Background In addition to their multilineage potential, mesenchymal stem cells (MSCs) have a broad range of functions from tissue regeneration to immunomodulation. MSCs have the ability to modulate the immune response and change the progression of different inflammatory and autoimmune disor...

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Bibliographic Details
Main Authors: Ghada Beldi, Maryam Khosravi, Mohamed Essameldin Abdelgawad, Benoît L. Salomon, Georges Uzan, Houda Haouas, Sina Naserian
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Immune regulation
Tolerance induction
Regulatory T cells
TNFα/TNFR2 signaling pathway
Immune checkpoint
Online Access:http://link.springer.com/article/10.1186/s13287-020-01740-5

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http://link.springer.com/article/10.1186/s13287-020-01740-5

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