Signalling pathways implicated in early mammary gland morphogenesis and breast cancer.

Specification of mammary epithelial cell fate occurs during embryogenesis as cells aggregate to form the mammary anlage. Within the embryonic mammary bud, a population of epithelial cells exists that will subsequently proliferate to form a ductal tree filling the stromal compartment, and which can p...

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Bibliographic Details
Main Authors: Beatrice Howard, Alan Ashworth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-08-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.0020112