Roles of CD34+ cells and ALK5 signaling in the reconstruction of seminiferous tubule-like structures in 3-D re-aggregate culture of dissociated cells from neonatal mouse testes.

Tissue reconstruction in vitro can provide, if successful, a refined and simple system to analyze the underlying mechanisms that drive the morphogenesis and maintain the ordered structure. We have recently succeeded in reconstruction of seminiferous cord-like and tubule-like structures using 3-D re-...

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Bibliographic Details
Main Authors: Shin-Ichi Abe, Kazuko Abe, Jidong Zhang, Tomoaki Harada, Go Mizumoto, Hiroki Oshikawa, Haruhiko Akiyama, Kenji Shimamura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5708723?pdf=render