Defining a Methylation Signature Associated With Operational Tolerance in Kidney Transplant Recipients

Defining a Methylation Signature Associated With Operational Tolerance in Kidney Transplant Recipients

Operational tolerance after kidney transplantation is defined as stable graft acceptance without the need for immunosuppression therapy. However, it is not clear which cellular and molecular pathways are driving tolerance in these patients. We performed genome-wide analysis of DNA methylation in per...

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Bibliographic Details
Main Authors: Ramon M. Rodriguez, María P. Hernández-Fuentes, Viviana Corte-Iglesias, María Laura Saiz, Juan José Lozano, Ana R. Cortazar, Isabel Mendizabal, María Luisa Suarez-Fernandez, Eliecer Coto, Antonio López-Vázquez, Carmen Díaz-Corte, Ana M. Aransay, Carlos López-Larrea, Beatriz Suarez-Álvarez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
epigenetics
DNA methylation
operational tolerance
kidney transplant
rejection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.709164/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.709164/full

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