Interaction of ASK1 and the β-amyloid precursor protein in a stress-signaling complex

Interaction of ASK1 and the β-amyloid precursor protein in a stress-signaling complex

The amyloid precursor protein (APP) is a type I transmembrane protein translocated to neuronal terminals, whose function is still unknown. The C-terminus of APP mediates its interaction with cellular adaptor and signaling proteins, some of which signal to the stress-activated protein kinase (SAPK) p...

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Bibliographic Details
Main Authors: Veronica Galvan, Surita Banwait, Patricia Spilman, Olivia F. Gorostiza, Alyson Peel, Marina Ataie, Danielle Crippen, Wei Huang, Gurleen Sidhu, Hidenori Ichijo, Dale E. Bredesen
Format: Article
Language:English
Published: Elsevier 2007-10-01
Series:Neurobiology of Disease
Subjects:
Amyloid precursor protein
Apoptosis signaling kinase
Stress signaling complex
Neurodegeneration
Alzheimer’s disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107001349

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http://www.sciencedirect.com/science/article/pii/S0969996107001349

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