Blood-brain barrier dysfunction significantly correlates with serum matrix metalloproteinase-7 (MMP-7) following traumatic brain injury

Blood-brain barrier dysfunction significantly correlates with serum matrix metalloproteinase-7 (MMP-7) following traumatic brain injury

Objectives: To determine if radiological evidence of blood brain barrier (BBB) dysfunction, measured using Dynamic Contrast Enhanced MRI (DCE-MRI), correlates with serum matrix metalloproteinase (MMP) levels in traumatic brain injury (TBI) patients, and thereby, identify a potential biomarker for BB...

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Bibliographic Details
Main Authors: Paul Nichols, Javier Urriola, Stephanie Miller, Tracey Bjorkman, Kate Mahady, Viktor Vegh, Fatima Nasrallah, Craig Winter
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:NeuroImage: Clinical
Subjects:
Traumatic brain injury
Blood brain barrier
Matrix metalloproteinase
Dynamic contrast enhanced magnetic resonance imaging
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213158221001856

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http://www.sciencedirect.com/science/article/pii/S2213158221001856

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