Does Long-Term High Fat Diet Always Lead to Smaller Hippocampi Volumes, Metabolite Concentrations, and Worse Learning and Memory? A Magnetic Resonance and Behavioral Study in Wistar Rats.

Obesity is a worldwide epidemic with more than 600 million affected individuals. Human studies have demonstrated some alterations in brains of otherwise healthy obese individuals and elevated risk of neurodegenerative disease of old age; these studies have also pointed to slightly diminished memory...

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Main Authors: Zuzanna Setkowicz, Agata Gaździńska, Joanna J Osoba, Karolina Karwowska, Piotr Majka, Jarosław Orzeł, Bartosz Kossowski, Piotr Bogorodzki, Krzysztof Janeczko, Mariusz Wyleżoł, Stefan P Gazdzinski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4598109?pdf=render