HIV cure strategies: how good must they be to improve on current antiretroviral therapy?

We examined efficacy, toxicity, relapse, cost, and quality-of-life thresholds of hypothetical HIV cure interventions that would make them cost-effective compared to life-long antiretroviral therapy (ART).We used a computer simulation model to assess three HIV cure strategies: Gene Therapy, Chemother...

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Bibliographic Details
Main Authors: Paul E Sax, Alexis Sypek, Bethany K Berkowitz, Bethany L Morris, Elena Losina, A David Paltiel, Kathleen A Kelly, George R Seage, Rochelle P Walensky, Milton C Weinstein, Joseph Eron, Kenneth A Freedberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4232561?pdf=render