A measure of the broad substrate specificity of enzymes based on 'duplicate' catalytic residues.

The ability of an enzyme to select and act upon a specific class of compounds with unerring precision and efficiency is an essential feature of life. Simultaneously, these enzymes often catalyze the reaction of a range of similar substrates of the same class, and also have promiscuous activities on...

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Bibliographic Details
Main Authors: Sandeep Chakraborty, Bjarni Ásgeirsson, Basuthkar J Rao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3500292?pdf=render