Continuity of transcriptomes among colorectal cancer subtypes based on meta-analysis

Abstract Background Previous approaches to defining subtypes of colorectal carcinoma (CRC) and other cancers based on transcriptomes have assumed the existence of discrete subtypes. We analyze gene expression patterns of colorectal tumors from a large number of patients to test this assumption and p...

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Bibliographic Details
Main Authors: Siyuan Ma, Shuji Ogino, Princy Parsana, Reiko Nishihara, Zhirong Qian, Jeanne Shen, Kosuke Mima, Yohei Masugi, Yin Cao, Jonathan A. Nowak, Kaori Shima, Yujin Hoshida, Edward L. Giovannucci, Manish K. Gala, Andrew T. Chan, Charles S. Fuchs, Giovanni Parmigiani, Curtis Huttenhower, Levi Waldron
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Genome Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13059-018-1511-4