Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position

New riminophenazines with pyrimidine and pyrazine substituents at the 2-position were successfully synthesized. The key step is the 2-N-arylation of riminophenazines with pyrimidine and pyrazine. The optimized reaction conditions involve the use of a Pd2(dba)3/DPPF/Cs2CO3/toluene combination.

Bibliographic Details
Main Authors: Haihong Huang, Dali Yin, Xiaojian Wang, Chun Li, Hao Zhang, Gang Zhang
Format: Article
Language:English
Published: MDPI AG 2011-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/8/6985/