Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position

Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position

New riminophenazines with pyrimidine and pyrazine substituents at the 2-position were successfully synthesized. The key step is the 2-N-arylation of riminophenazines with pyrimidine and pyrazine. The optimized reaction conditions involve the use of a Pd2(dba)3/DPPF/Cs2CO3/toluene combination.

Bibliographic Details
Main Authors: Haihong Huang, Dali Yin, Xiaojian Wang, Chun Li, Hao Zhang, Gang Zhang
Format: Article
Language:English
Published: MDPI AG 2011-08-01
Series:Molecules
Subjects:
riminophenazine
N-arylation
palladium catalyst
Online Access:http://www.mdpi.com/1420-3049/16/8/6985/
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spelling doaj-8fc9f75510494ff0ad59b8c291f9811b2020-11-24T22:15:05ZengMDPI AGMolecules1420-30492011-08-011686985699110.3390/molecules16086985Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N PositionHaihong HuangDali YinXiaojian WangChun LiHao ZhangGang ZhangNew riminophenazines with pyrimidine and pyrazine substituents at the 2-position were successfully synthesized. The key step is the 2-N-arylation of riminophenazines with pyrimidine and pyrazine. The optimized reaction conditions involve the use of a Pd2(dba)3/DPPF/Cs2CO3/toluene combination.http://www.mdpi.com/1420-3049/16/8/6985/riminophenazineN-arylationpalladium catalyst
collection DOAJ
language English
format Article
sources DOAJ
author Haihong Huang
Dali Yin
Xiaojian Wang
Chun Li
Hao Zhang
Gang Zhang
spellingShingle Haihong Huang
Dali Yin
Xiaojian Wang
Chun Li
Hao Zhang
Gang Zhang
Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position
Molecules
riminophenazine
N-arylation
palladium catalyst
author_facet Haihong Huang
Dali Yin
Xiaojian Wang
Chun Li
Hao Zhang
Gang Zhang
author_sort Haihong Huang
title Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position
title_short Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position
title_full Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position
title_fullStr Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position
title_full_unstemmed Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position
title_sort synthesis of new riminophenazines with pyrimidine and pyrazine substitution at the 2-n position
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2011-08-01
description New riminophenazines with pyrimidine and pyrazine substituents at the 2-position were successfully synthesized. The key step is the 2-N-arylation of riminophenazines with pyrimidine and pyrazine. The optimized reaction conditions involve the use of a Pd2(dba)3/DPPF/Cs2CO3/toluene combination.
topic riminophenazine
N-arylation
palladium catalyst
url http://www.mdpi.com/1420-3049/16/8/6985/
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AT daliyin synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition
AT xiaojianwang synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition
AT chunli synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition
AT haozhang synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition
AT gangzhang synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition
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