Allicin Alleviates Reticuloendotheliosis Virus-Induced Immunosuppression via ERK/Mitogen-Activated Protein Kinase Pathway in Specific Pathogen-Free Chickens

Allicin Alleviates Reticuloendotheliosis Virus-Induced Immunosuppression via ERK/Mitogen-Activated Protein Kinase Pathway in Specific Pathogen-Free Chickens

Reticuloendotheliosis virus (REV), a gammaretrovirus in the Retroviridae family, causes an immunosuppressive, oncogenic, and runting–stunting syndrome in multiple avian hosts. Allicin, the main effective component of garlic, has a broad spectrum of pharmacological properties. The hypothesis that all...

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Bibliographic Details
Main Authors: Liyuan Wang, Hongchao Jiao, Jingpeng Zhao, Xiaojuan Wang, Shuhong Sun, Hai Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
reticuloendotheliosis virus
allicin
mitogen-activated protein kinase
nuclear factor kappa B p65
oxidative stress
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01856/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01856/full

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