The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry

The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry

DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is the key regulator of the non-homologous end joining pathway of DNA double-strand break repair. We have previously reported that DNA-PKcs is required for maintaining chromosomal stability and mitosis progression. Our further investigations...

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Bibliographic Details
Main Authors: Kyung-Jong Lee, Zeng-Fu Shang, Yu-Fen Lin, Jingxin Sun, Keiko Morotomi-Yano, Debabrata Saha, Benjamin P.C. Chen
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558615000305

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http://www.sciencedirect.com/science/article/pii/S1476558615000305

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