Robust B Cell Responses Predict Rapid Resolution of Lyme Disease

Robust B Cell Responses Predict Rapid Resolution of Lyme Disease

Lyme disease (Borrelia burgdorferi infection) is increasingly recognized as a significant source of morbidity worldwide. Here, we show that blood plasmablasts and CD27− memory B cells are elevated in untreated Lyme disease, with higher plasmablast levels associated with more rapid resolution of clin...

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Bibliographic Details
Main Authors: Lisa K. Blum, Julia Z. Adamska, Dale S. Martin, Alison W. Rebman, Serra E. Elliott, Richard R. L. Cao, Monica E. Embers, John N. Aucott, Mark J. Soloski, William H. Robinson
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
Lyme disease
Borrelia
antibodies
plasmablasts
immune repertoire
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01634/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01634/full

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