Modeling transcriptional regulation using gene regulatory networks based on multi-omics data sources
Abstract Background Transcriptional regulation is complex, requiring multiple cis (local) and trans acting mechanisms working in concert to drive gene expression, with disruption of these processes linked to multiple diseases. Previous computational attempts to understand the influence of regulatory...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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BMC
2021-04-01
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| Series: | BMC Bioinformatics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12859-021-04126-3 |