Detection of gray matter microstructural changes in Alzheimer’s disease continuum using fiber orientation

Detection of gray matter microstructural changes in Alzheimer’s disease continuum using fiber orientation

Abstract Background This study aimed to investigate feasible gray matter microstructural biomarkers with high sensitivity for early Alzheimer’s disease (AD) detection. We propose a diffusion tensor imaging (DTI) measure, “radiality”, as an early AD biomarker. It is the dot product of the normal vect...

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Bibliographic Details
Main Authors: Peter Lee, Hang-Rai Kim, Yong Jeong, for the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Neurology
Subjects:
Alzheimer’s disease
Early diagnosis
Diffusion tensor imaging
Microstructure
Biomarkers
Online Access:http://link.springer.com/article/10.1186/s12883-020-01939-2

Internet

http://link.springer.com/article/10.1186/s12883-020-01939-2

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