Rapid State-Dependent Alteration in Kv3 Channel Availability Drives Flexible Synaptic Signaling Dependent on Somatic Subthreshold Depolarization

In many neurons, subthreshold depolarization in the soma can transiently increase action-potential (AP)-evoked neurotransmission via analog-to-digital facilitation. The mechanisms underlying this form of short-term synaptic plasticity are unclear, in part, due to the relative inaccessibility of the...

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Bibliographic Details
Main Authors: Matthew J.M. Rowan, Jason M. Christie
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Cell Reports
Subjects:
HCN
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717301389