Evaluation of Modulators of cAMP-Response in Terms of Their Impact on Cell Cycle and Mitochondrial Activity of Leishmania donovani

Evaluation of Modulators of cAMP-Response in Terms of Their Impact on Cell Cycle and Mitochondrial Activity of Leishmania donovani

With the identification of novel cAMP binding effector molecules in Trypanosoma, the role of cAMP in kinetoplastida parasites gained an intriguing breakthrough. Despite earlier demonstrations of the role of cAMP in the survival of Leishmania during macrophage infection, there is essential need to sp...

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Bibliographic Details
Main Authors: Amrita Saha, Anindita Bhattacharjee, Amit Vij, Pijush K. Das, Arijit Bhattacharya, Arunima Biswas
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
Leishmania
cAMP
cyclic nucleotide phosphodiesterase
cell cycle
motility
etazolate
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00782/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00782/full

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