Entamoeba histolytica Trophozoites Induce a Rapid Non-classical NETosis Mechanism Independent of NOX2-Derived Reactive Oxygen Species and PAD4 Activity

Neutrophil extracellular traps (NETs) are DNA fibers decorated with histones and antimicrobial proteins from cytoplasmic granules released into the extracellular space in a process denominated NETosis. The molecular pathways involved in NETosis have not been completely understood. Classical NETosis...

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Bibliographic Details
Main Authors: César Díaz-Godínez, Zayda Fonseca, Mario Néquiz, Juan P. Laclette, Carlos Rosales, Julio C. Carrero
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
ROS
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00184/full