Aberrant control of NF-κB in cancer permits transcriptional and phenotypic plasticity, to curtail dependence on host tissue: molecular mode
The role of the transcription factor NF-κB in shaping the cancer microenvironment is becoming increasingly clear. Inflammation alters the activity of enzymes that modulate NF-κB function, and causes extensive changes in genomic chromatin that ultimately drastically alter cell-specific gene expressio...
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| Format: | Article |
| Language: | English |
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China Anti-Cancer Association
2017-06-01
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| Series: | Cancer Biology & Medicine |
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| Online Access: | http://www.cancerbiomed.org/index.php/cocr/article/view/1047 |