Trilobatin ameliorates insulin resistance through IRS-AKT-GLUT4 signaling pathway in C2C12 myotubes and ob/ob mice

Abstract Background Trilobatin, a natural compound, has been found to exhibit anti-diabetic properties in high-fat diet (HFD) and streptozotocin (STZ) induced type 2 diabetic mice. But up to now no research has been reported on the effect of trilobatin on insulin resistance in peripheral tissues. He...

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Bibliographic Details
Main Authors: Min Liu, Lujing Wang, Xigan Li, Yucui Wu, Fei Yin, Jianhui Liu
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Chinese Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13020-020-00390-2