Silica-Triggered Autoimmunity in Lupus-Prone Mice Blocked by Docosahexaenoic Acid Consumption.

Occupational exposure to respirable crystalline silica (cSiO2, quartz) is etiologically linked to systemic lupus erythematosus (lupus) and other human autoimmune diseases (ADs). In the female NZBWF1 mouse, a widely used animal model that is genetically prone to lupus, short-term repeated intranasal...

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Bibliographic Details
Main Authors: Melissa A Bates, Christina Brandenberger, Ingeborg I Langohr, Kazuyoshi Kumagai, Adam L Lock, Jack R Harkema, Andrij Holian, James J Pestka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4981380?pdf=render