Extracellular Matrix Features Discriminate Aggressive HER2-Positive Breast Cancer Patients Who Benefit from Trastuzumab Treatment

Extracellular Matrix Features Discriminate Aggressive HER2-Positive Breast Cancer Patients Who Benefit from Trastuzumab Treatment

We previously identified an extracellular matrix (ECM) gene expression pattern in breast cancer (BC), called ECM3, characterized by a high expression of genes encoding structural ECM proteins. Since ECM is reportedly implicated in response to therapy of BCs, the aim of this work is to investigate th...

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Bibliographic Details
Main Authors: Ilona Rybinska, Marco Sandri, Francesca Bianchi, Rosaria Orlandi, Loris De Cecco, Patrizia Gasparini, Manuela Campiglio, Biagio Paolini, Lucia Sfondrini, Elda Tagliabue, Tiziana Triulzi
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
extracellular matrix
her2 positive breast cancer
gene expression
ecm3
collagen
trastuzumab
Online Access:https://www.mdpi.com/2073-4409/9/2/434

Internet

https://www.mdpi.com/2073-4409/9/2/434

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