Histopathological comparison of Kearns-Sayre syndrome and PGC-1α-deficient mice suggests a novel concept for vacuole formation in mitochondrial encephalopathy

Histopathological comparison of Kearns-Sayre syndrome and PGC-1α-deficient mice suggests a novel concept for vacuole formation in mitochondrial encephalopathy

Despite the current hypotheses about myelinic and astrocytic ion-dyshomeostasis underlying white (WM) and grey matter (GM) vacuolation in mitochondrial encephalopathies, there is a paucity of data on the exact mechanism of vacuole formation. To revisit the concepts of vacuole formation associated wi...

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Bibliographic Details
Main Authors: Levente Szalardy, Mate Molnar, Rita Torok, Denes Zadori, Laszlo Vecsei, Peter Klivenyi, Paweł Piotr Liberski, Gabor Geza Kovacs
Format: Article
Language:English
Published: Termedia Publishing House 2016-03-01
Series:Folia Neuropathologica
Subjects:
<i>Kearns-Sayre syndrome
PGC-1α
mitochondrial encephalopathy
vacuole
myelin
oligodendrocyte</i>
Online Access:https://www.termedia.pl/Histopathological-comparison-of-Kearns-Sayre-syndrome-and-PGC-1-deficient-mice-suggests-a-novel-concept-for-vacuole-formation-in-mitochondrial-encephalopathy,20,27226,1,1.html

Internet

https://www.termedia.pl/Histopathological-comparison-of-Kearns-Sayre-syndrome-and-PGC-1-deficient-mice-suggests-a-novel-concept-for-vacuole-formation-in-mitochondrial-encephalopathy,20,27226,1,1.html

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