Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases

Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases

Parabens are effective preservatives widely used in cosmetic products and processed food, with high human exposure. Recent evidence suggests that parabens exert estrogenic effects. This work investigated the potential interference of parabens with the estrogen-activating enzyme 17β-hydroxysteroid de...

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Bibliographic Details
Main Authors: Roger T. Engeli, Simona R. Rohrer, Anna Vuorinen, Sonja Herdlinger, Teresa Kaserer, Susanne Leugger, Daniela Schuster, Alex Odermatt
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:International Journal of Molecular Sciences
Subjects:
17β-hydroxysteroid dehydrogenase
estrogen
xenobiotic
endocrine disrupting chemical
in silico
in vitro
Online Access:https://www.mdpi.com/1422-0067/18/9/2007

Internet

https://www.mdpi.com/1422-0067/18/9/2007

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