Automated image analysis system for studying cardiotoxicity in human pluripotent stem cell-Derived cardiomyocytes

Automated image analysis system for studying cardiotoxicity in human pluripotent stem cell-Derived cardiomyocytes

Abstract Background Cardiotoxicity, characterized by severe cardiac dysfunction, is a major problem in patients treated with different classes of anticancer drugs. Development of predictable human-based models and assays for drug screening are crucial for preventing potential drug-induced adverse ef...

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Bibliographic Details
Main Authors: Lu Cao, Andries D. van der Meer, Fons J. Verbeek, Robert Passier
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Bioinformatics
Subjects:
Cardiotoxicity
hiPSC-derived cardiomyocytes
High-throughput screening
Image analysis
Phenotype quantification
Online Access:http://link.springer.com/article/10.1186/s12859-020-3466-1

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http://link.springer.com/article/10.1186/s12859-020-3466-1

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