Automated image analysis system for studying cardiotoxicity in human pluripotent stem cell-Derived cardiomyocytes
Abstract Background Cardiotoxicity, characterized by severe cardiac dysfunction, is a major problem in patients treated with different classes of anticancer drugs. Development of predictable human-based models and assays for drug screening are crucial for preventing potential drug-induced adverse ef...
Main Authors: | Lu Cao, Andries D. van der Meer, Fons J. Verbeek, Robert Passier |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-05-01
|
Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-020-3466-1 |
Similar Items
-
Activation of AMPK Promotes Maturation of Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells
by: Liang Ye, et al.
Published: (2021-03-01) -
An integrated characterization of contractile, electrophysiological, and structural cardiotoxicity of Sophora tonkinensis Gapnep. in human pluripotent stem cell-derived cardiomyocytes
by: Ruiying Wang, et al.
Published: (2019-01-01) -
Uninterrupted monitoring of drug effects in human-induced pluripotent stem cell-derived cardiomyocytes with bioluminescence Ca2+ microscopy
by: Kazushi Suzuki, et al.
Published: (2018-05-01) -
Modeling polymorphic ventricular tachycardia at rest using patient-specific induced pluripotent stem cell-derived cardiomyocytes
by: Yvonne Sleiman, et al.
Published: (2020-10-01) -
Patient-Derived Induced Pluripotent Stem Cell-Based Models in Parkinson’s Disease for Drug Identification
by: Georgia Kouroupi, et al.
Published: (2020-09-01)