A Polymorphism at the Translation Start Site of the Vitamin D Receptor Gene Is Associated with the Response to Anti-Osteoporotic Therapy in Postmenopausal Women from Southern Italy

A Polymorphism at the Translation Start Site of the Vitamin D Receptor Gene Is Associated with the Response to Anti-Osteoporotic Therapy in Postmenopausal Women from Southern Italy

The present study investigated the effect of two single nucleotide polymorphisms (SNPs) of the vitamin D receptor (VDR) gene, rs1544410 A/G and rs2228570 C/T, in modulating bone mineral density (BMD) and the response to treatment with bisphosphonates or strontium ranelate in postmenopausal osteoporo...

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Bibliographic Details
Main Authors: Valeria Conti, Giusy Russomanno, Graziamaria Corbi, Giuseppe Toro, Vittorio Simeon, Walter Filippelli, Nicola Ferrara, Michela Grimaldi, Valeria D'Argenio, Nicola Maffulli, Amelia Filippelli
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:International Journal of Molecular Sciences
Subjects:
pharmacogenetics
postmenopausal osteoporosis
bisphosphonate
bone mineral density
VDR genotype
rs1544410
rs2228570
Online Access:http://www.mdpi.com/1422-0067/16/3/5452

Internet

http://www.mdpi.com/1422-0067/16/3/5452

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