Review: Local Tumor Necrosis Factor-α Inhibition in Inflammatory Bowel Disease

Review: Local Tumor Necrosis Factor-α Inhibition in Inflammatory Bowel Disease

Crohn’s disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBD) characterized by intestinal inflammation. Increased intestinal levels of the proinflammatory cytokine tumor necrosis factor-α (TNF-α) are associated with disease activity and severity. Anti-TNF-α therapy is admini...

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Bibliographic Details
Main Authors: Bahez Gareb, Antonius T. Otten, Henderik W. Frijlink, Gerard Dijkstra, Jos G. W. Kosterink
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Pharmaceutics
Subjects:
inflammatory bowel disease
tumor necrosis factor-α
local
topical
site-specific
drug targeting
Online Access:https://www.mdpi.com/1999-4923/12/6/539

Internet

https://www.mdpi.com/1999-4923/12/6/539

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