Emergence of cooperative bistability and robustness of gene regulatory networks.

Gene regulatory networks (GRNs) are complex systems in which many genes regulate mutually to adapt the cell state to environmental conditions. In addition to function, the GRNs possess several kinds of robustness. This robustness means that systems do not lose their functionality when exposed to dis...

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Bibliographic Details
Main Authors: Shintaro Nagata, Macoto Kikuchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007969