DEAD-Box Helicase DDX6 Facilitated RIG-I-Mediated Type-I Interferon Response to EV71 Infection

DEAD-Box Helicase DDX6 Facilitated RIG-I-Mediated Type-I Interferon Response to EV71 Infection

Previous studies have shown that DEAD (Glu-Asp-Ala-Glu)-box RNA helicases play important roles in viral infection, either as cytosolic sensors of pathogenic molecules or as essential host factors against viral infection. In the current study, we found that DDX6, an RNA helicase belonging to the DEAD...

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Bibliographic Details
Main Authors: Rui Zhang, Min Cheng, Bingxin Liu, Meng Yuan, Deyan Chen, Yujiong Wang, Zhiwei Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
EV71
DDX6
RIG-I
Innate immune response
2Apro
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.725392/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.725392/full

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