Synthesis of Novel Fluorinated Xanthine Derivatives with High Adenosine A<sub>2B</sub> Receptor Binding Affinity

Synthesis of Novel Fluorinated Xanthine Derivatives with High Adenosine A<sub>2B</sub> Receptor Binding Affinity

The G protein-coupled adenosine A<sub>2B</sub> receptor is suggested to be involved in various pathological processes accompanied by increased levels of adenosine as found in inflammation, hypoxia, and cancer. Therefore, the adenosine A<sub>2B</sub> receptor is currently in f...

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Bibliographic Details
Main Authors: Marcel Lindemann, Sladjana Dukic-Stefanovic, Sonja Hinz, Winnie Deuther-Conrad, Rodrigo Teodoro, Cathleen Juhl, Jörg Steinbach, Peter Brust, Christa E. Müller, Barbara Wenzel
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceuticals
Subjects:
xanthine
adenosine A<sub>2B</sub> receptor
adenosine
PSB-603
Online Access:https://www.mdpi.com/1424-8247/14/5/485

Internet

https://www.mdpi.com/1424-8247/14/5/485

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