Circular RNA hsa_circ_0068871 regulates FGFR3 expression and activates STAT3 by targeting miR-181a-5p to promote bladder cancer progression

Circular RNA hsa_circ_0068871 regulates FGFR3 expression and activates STAT3 by targeting miR-181a-5p to promote bladder cancer progression

Abstract Background FGFR3 plays an important role in the development of bladder cancer (BCa). Hsa_circ_0068871 is a circRNA generated from several exons of FGFR3. However, the potential functional role of hsa_circ_0068871 in BCa remains largely unknown. Here we aim to evaluate the role of hsa_circ_0...

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Bibliographic Details
Main Authors: Weipu Mao, Xin Huang, Longsheng Wang, Ziwei Zhang, Mengnan Liu, Yan Li, Ming Luo, Xudong Yao, Jie Fan, Jiang Geng
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Bladder cancer
hsa_circ_0068871
miR-181a-5p
FGFR3
STAT3
Online Access:http://link.springer.com/article/10.1186/s13046-019-1136-9

Internet

http://link.springer.com/article/10.1186/s13046-019-1136-9

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