Early epidemiological assessment of the virulence of emerging infectious diseases: a case study of an influenza pandemic.

BACKGROUND:The case fatality ratio (CFR), the ratio of deaths from an infectious disease to the number of cases, provides an assessment of virulence. Calculation of the ratio of the cumulative number of deaths to cases during the course of an epidemic tends to result in a biased CFR. The present stu...

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Bibliographic Details
Main Authors: Hiroshi Nishiura, Don Klinkenberg, Mick Roberts, Johan A P Heesterbeek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2729920?pdf=render