Recipient's genetic R702W NOD2 variant is associated with an increased risk of bacterial infections after orthotopic liver transplantation.

INTRODUCTION: Orthotopic liver transplantation (OLT) is accompanied by a significant postoperative infection risk. Immunosuppression to prevent rejection increases the susceptibility to infections, mainly by impairing the adaptive immune system. Genetic polymorphisms in the lectin complement pathway...

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Bibliographic Details
Main Authors: Marcel Janse, Bert-Jan F de Rooij, Bart van Hoek, Arie P van den Berg, Robert J Porte, Hans Blokzijl, Minneke J Coenraad, Bouke G Hepkema, Alexander F Schaapherder, Jan Ringers, Rinse K Weersma, Hein W Verspaget
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3747080?pdf=render