RasGAP-derived peptide GAP159 enhances cisplatin-induced cytotoxicity and apoptosis in HCT116 cells

To increase the efficacy of currently used anti-cancer genotoxins, one of the current efforts is to find agents that can sensitize cancer cells to genotoxins so that the efficacious doses of genotoxins can be lowered to reduce deleterious side-effects. In this study, we reported that a synthetic Ras...

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Bibliographic Details
Main Authors: Hao Zhang, Shenghua Zhang, Hongwei He, Caixia Zhang, Yi Chen, Dongke Yu, Jianhua Chen, Rongguang Shao
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383514000240