Free Chlorine and Peroxynitrite Alter the Capsid Structure of Human Norovirus GII.4 and Its Capacity to Bind Histo-Blood Group Antigens

Free Chlorine and Peroxynitrite Alter the Capsid Structure of Human Norovirus GII.4 and Its Capacity to Bind Histo-Blood Group Antigens

Human noroviruses (HuNoVs) are one of the leading causes of acute gastroenteritis worldwide. HuNoVs are frequently detected in water and foodstuffs. Free chlorine and peroxynitrite (ONOO−) are two oxidants commonly encountered by HuNoVs in humans or in the environment during their natural life cycle...

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Bibliographic Details
Main Authors: Manon Chassaing, Guillaume Bastin, Maëlle Robin, Didier Majou, Gaël Belliot, Alexis de Rougemont, Nicolas Boudaud, Christophe Gantzer
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Microbiology
Subjects:
norovirus
virus-like particles
viral protein
histo-blood group antigens
free chlorine
peroxynitrite
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.662764/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.662764/full

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