Increased expression of Rififylin in a <330kb congenic strain is linked to impaired endosomal recycling in proximal tubules

Increased expression of Rififylin in a <330kb congenic strain is linked to impaired endosomal recycling in proximal tubules

Cell surface proteins are internalized into the cell through endocytosis and either degraded within lysosomes or recycled back to the plasma membrane. While perturbations in endosomal internalization are known to modulate renal function, it is not known whether similar alterations in recycling affec...

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Bibliographic Details
Main Authors: Bina eJoe, Kathirvel eGopalakrishnan, Sivarajan eKumarasamy, Yanling eYan, Jiang eLiu, Andrea L Kalinoski, Anbarasi eKodandapani, Phyllis eFarms
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Genetics
Subjects:
Genetics
Hypertension
Proteinuria
Quantitative Trait Loci
Association mapping
gene
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00138/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00138/full

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