Precise determination of input-output mapping for multimodal gene circuits using data from transient transfection.
The mapping of molecular inputs to their molecular outputs (input/output, I/O mapping) is an important characteristic of gene circuits, both natural and synthetic. Experimental determination of such mappings for synthetic circuits is best performed using stably integrated genetic constructs. In mamm...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-11-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1008389 |