Pro-apoptotic kinases levels in cerebrospinal fluid as potential future biomarkers in Alzheimer’s Disease

AAlzheimer’s disease (AD) is characterized by the accumulation of Aβ peptides, hyperphosphorylated tau proteins and neuronal loss in the brain of affected patients. The causes of neurodegeneration in AD are not clear but apoptosis could be one of the cell death mechanisms. According to the amyloid h...

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Bibliographic Details
Main Authors: Claire ePAQUET, Julien eDUMURGIER, Jacques eHUGON
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Neurology
Subjects:
JNK
PKR
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2015.00168/full