Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment scores
<p>Abstract</p> <p>Background</p> <p>Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic data. Two statistical models have been proposed. In the asymptotic...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-08-01
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Series: | BMC Bioinformatics |
Online Access: | http://www.biomedcentral.com/1471-2105/9/332 |