Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment scores

<p>Abstract</p> <p>Background</p> <p>Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic data. Two statistical models have been proposed. In the asymptotic...

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Bibliographic Details
Main Authors: Maréchal Eric, Bastien Olivier
Format: Article
Language:English
Published: BMC 2008-08-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/9/332