Oseltamivir-resistant pandemic H1N1/2009 influenza virus possesses lower transmissibility and fitness in ferrets.

The neuraminidase (NA) inhibitor oseltamivir offers an important immediate option for the control of influenza, and its clinical use has increased substantially during the recent H1N1 pandemic. In view of the high prevalence of oseltamivir-resistant seasonal H1N1 influenza viruses in 2007-2008, ther...

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Bibliographic Details
Main Authors: Susu Duan, David A Boltz, Patrick Seiler, Jiang Li, Karoline Bragstad, Lars P Nielsen, Richard J Webby, Robert G Webster, Elena A Govorkova
Format: Article
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2912389?pdf=render