The Role of M. leprae Hsp65 Protein and Peptides in the Pathogenesis of Uveitis

Experimental autoimmune uveitis (EAU) is a well established model for immune-mediated organ-specific disease. Our group has recently shown that the M. leprae Hsp65 aggravated the uveitis in mice; in the present study, we evaluated the action of M. leprae  K409A mutant protein and the synthetic pepti...

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Main Authors: Alessandra Gonçalves Commodaro, Eliana Blini Marengo, Jean Pierre S. Peron, Wesley Brandao, Christina Arslanian, Robson Lopes Melo, Estevam J. Baldon, Rubens Belfort, Osvaldo Augusto Sant'Anna, Luiz Vicente Rizzo
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Autoimmune Diseases
Online Access:http://dx.doi.org/10.1155/2012/197648