Where Does the Alignment Score Distribution Shape Come from?

Alignment algorithms are powerful tools for searching for homologous proteins in databases, providing a score for each sequence present in the database. It has been well known for 20 years that the shape of the score distribution looks like an extreme value distribution. The extremely large number o...

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Bibliographic Details
Main Authors: Philippe Ortet, Olivier Bastien
Format: Article
Language:English
Published: SAGE Publishing 2010-01-01
Series:Evolutionary Bioinformatics
Online Access:https://doi.org/10.4137/EBO.S5875