Diesel exhaust particulate induces pulmonary and systemic inflammation in rats without impairing endothelial function <it>ex vivo </it>or <it>in vivo</it>

<p>Abstract</p> <p>Background</p> <p>Inhalation of diesel exhaust impairs vascular function in man, by a mechanism that has yet to be fully established. We hypothesised that pulmonary exposure to diesel exhaust particles (DEP) would cause endothelial dysfunction in rats...

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Bibliographic Details
Main Authors: Robertson Sarah, Gray Gillian A, Duffin Rodger, McLean Steven G, Shaw Catherine A, Hadoke Patrick WF, Newby David E, Miller Mark R
Format: Article
Language:English
Published: BMC 2012-04-01
Series:Particle and Fibre Toxicology
Subjects:
Online Access:http://www.particleandfibretoxicology.com/content/9/1/9