Inducible expression of noggin selectively expands neural progenitors in the adult SVZ

Multipotent, self-renewing stem cells are present throughout the developing nervous system remaining in discrete regions of the adult brain. In the subventricular zone (SVZ) signaling molecules, including the bone morphogenetic proteins and their secreted inhibitor, noggin appear to play a critical...

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Bibliographic Details
Main Authors: M. Morell, Yao-chang Tsan, K. Sue O'Shea
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506114001378