Lynch Syndrome: Its Impact on Urothelial Carcinoma

Lynch Syndrome: Its Impact on Urothelial Carcinoma

Lynch syndrome, known as hereditary nonpolyposis colorectal cancer (HNPCC), is an autosomal-dominant familial cancer syndrome with an increased risk for urothelial cancer (UC). Mismatch repair (MMR) deficiency, due to pathogenic variants in <i>MLH1</i>, <i>MSH2</i>, <i>...

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Bibliographic Details
Main Authors: Andrea Katharina Lindner, Gert Schachtner, Gennadi Tulchiner, Martin Thurnher, Gerold Untergasser, Peter Obrist, Iris Pipp, Fabian Steinkohl, Wolfgang Horninger, Zoran Culig, Renate Pichler
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
Lynch syndrome
urothelial cancer
upper urinary tract
DNA mismatch repair genes
MMR
microsatellite instability
Online Access:https://www.mdpi.com/1422-0067/22/2/531

Internet

https://www.mdpi.com/1422-0067/22/2/531

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