Epistatic interactions modulate the evolution of mammalian mitochondrial respiratory complex components
<p>Abstract</p> <p>Background</p> <p>The deleterious effect of a mutation can be reverted by a second-site interacting residue. This is an epistatic compensatory process explaining why mutations that are deleterious in some species are tolerated in phylogenetically rela...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-06-01
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Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/10/266 |